Zhejiang Tailin Biotechnology Co., Ltd
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Penicillinase/cephalosporinase/metalloenzyme/glycopeptidase/gold spectrum specific enzyme/macrolide enzyme
Enzyme series products such as penicillin enzyme, cephalosporin enzyme, metalloenzyme, glycopeptidase, golden spectrum special enzyme, and macrolide e
Product details
Penicillinase/cephalosporinase/metalloenzyme/glycopeptidase/gold spectrum specific enzyme/macrolide enzyme
青霉素酶/头孢菌素酶/金属酶/糖肽酶/金色谱特殊酶/大环内酯酶
青霉素酶/头孢菌素酶/金属酶/糖肽酶/金色谱特殊酶/大环内酯酶

Enzyme series products such as penicillin enzyme, cephalosporin enzyme, metalloenzyme, glycopeptidase, golden spectrum special enzyme, and macrolide enzyme are used for sterile testing and microbial limit testing of antibiotic products.

penicillinase
Penicillinase is a type of β - lactase, which can be highly active by constructing transgenic plasmids and expressing them through engineering bacterial culture. The activity can reach 5 million units per milliliter, which is superior to the extracellular enzymes fermented by traditional Bacillus cereus.


Characteristics: High activity, strong bactericidal effect on penicillin antibiotics.


[Scope of Application]

1. This product can effectively hydrolyze β - lactam antibiotics, including penicillin G, ampicillin, amoxicillin, piperacillin, carbenicillin, ticarcillin, furosemide, meropenem, cephalosporin, etc;

2. Can be used for sterility testing in the inspection of β - lactam antibiotics for injection;

3. It can be used for microbial limit testing in the testing of oral and other β - lactam antibiotics.


Enzyme type Dosage form content enzyme activity package
penicillinase Water based type 3mL ≥ 15 million units/bottle 10 bottles/box
penicillinase Water based type 5mL ≥ 15 million units/bottle 10 bottles/box


cephalosporinase

Cefotaxinase belongs to β - lactams and is extracted through recombinant genes and proteins. The principle is to inactivate the antibacterial properties of penicillin and cephalosporins, which are more effective than penicillin enzymes and general cephalosporin enzymes.


Water based characteristics: Each bottle undergoes a batch of sterile tests and can be used directly without the need for reconstitution.

Freeze dried type features: easy to transport, requires adding 5mL of sterile water to dissolve and conduct a batch of sterile tests.

[Scope of Application]

1. This product can effectively hydrolyze cephalosporin antibiotics, including: cefuroxime, cefradine, cefaclor, cefuroxime, cefoperazone, cefotaxime, ceftriaxone, etc;

2. Can be used for sterile testing in the inspection of cephalosporin antibiotics raw materials and injectable cephalosporin antibiotics drugs;

3. It can be used for microbial limit testing in the inspection of oral and other cephalosporin antibiotics.


Enzyme type Dosage form content enzyme activity package
cephalosporinase Water based type 7mL ≥ 2 million units/bottle 10 bottles/box
cephalosporinase Water based type 5mL ≥ 2 million units/bottle 10 bottles/box
cephalosporinase
Freeze dried type
-
≥ 2 million units/bottle 10 bottles/box


Metalloenzyme

Metalloenzymes belong to β - lactams and are used to inactivate carbapenems (penems) antibiotics, with better efficacy than penicillinases.


Features: Easy to transport, requires adding 5mL of sterile water to dissolve and conduct a batch of sterile tests.

[Scope of Application]

1. This product can effectively hydrolyze β - lactam antibiotics, especially carbapenems (penems);

2. Can be used for sterility testing in the inspection of β - lactam antibiotics for injection;

3. It can be used for microbial limit testing in the testing of oral and other β - lactam antibiotics.


Enzyme type Dosage form content enzyme activity package
Metalloenzyme Freeze dried type - ≥ 2 million units/bottle 10 bottles/box


Glycopeptidase

Glycopeptidase is purified through recombinant genes, mainly by opening the amide bonds of vancomycin and teicoplanin, causing them to lose their antibacterial properties and achieve inactivation.


Features: Easy to transport, requires adding 5mL of sterile water to dissolve and conduct a batch of sterile tests.

[Scope of Application]

1. This product can effectively inactivate vancomycin and teicoplanin;

2. Can be used for sterile testing of vancomycin and teicoplanin for injection;

3. Can be used for microbial limit testing of oral and other vancomycin and teicoplanin.


Enzyme type Dosage form content enzyme activity package
Glycopeptidase Freeze dried type - ≥ 100 units/bottle 10 bottles/box


Golden spectrum special enzyme

The golden spectrum special enzyme is used to inactivate polymyxin B sulfate.


[Scope of Application]

1. This product can effectively inactivate polymyxin B sulfate;

2. Can be used for sterile testing of injectable polymyxin B sulfate;

3. Can be used for microbial limit testing of oral and other sulfated polymyxin B.


Enzyme type Dosage form content package
Golden spectrum special enzyme Water based type 1mL 10 bottles/box


Macrocyclic lactonase

Macrolide enzyme is a genetically modified recombinant protein that is water-soluble and has a molecular weight of around 70000. The principle is to inactivate the antibacterial activity of macrolides. Used for sterility testing and microbial limit testing of macrolide antibiotics.


[Scope of Application]

1. This product can effectively inactivate macrolide antibiotics;

2. Can be used for sterile testing of injectable macrolide antibiotics;

3. Can be used for microbial limit testing of oral and other macrolide antibiotics.


Enzyme type Dosage form enzyme activity package
Macrocyclic lactonase Freeze dried type ≥ 10 units/bottle 10 bottles/box


Product technical information may change due to product upgrades without prior notice, and the final interpretation rights belong to Tailin.

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